RNAapt3D

Detail of monad0045

Aptamer Detail

monad ID: monad0045

Length: 40

Target Molecule: NGF (P01138)

Sequence: GGGUCCUGCUGCGUAGUUUCCGUCUGCGUGGCUGUUACCC

Adaptation Disease: Pain

Product Name: RBM-004

Phase: PC

Remark: It is expected that this aptamer blocks pain signals transmitted to the spinal cord and brain

Structure monad0045-1

Parameter: CentroidFold: McCaskill(BL) 2^2

Structure String: ((((.(.(((((((((.......))))))))).)..))))

Flip Position: ----------------*******-----------------

Tertiary Structure: Rascal: Model
Na+
Optimized Model
Modified Model
Mg2+
Optimized Model

Secondary Structure

Structure monad0045-2

Parameter: CentroidFold: McCaskill(BL) 2^5

Structure String: ((((.(.((((((((((....).))))))))).)..))))

Flip Position: -----------------****-------------------

Tertiary Structure: Rascal: Model
Na+
Optimized Model
Modified Model
Mg2+
Optimized Model

Secondary Structure

Structure monad0045-3

Parameter: CentroidFold: McCaskill(BL) 2^0

Structure String: ((((...(((((((((.......)))))))))....))))

Flip Position: -----------------*****-----------*------

Tertiary Structure: Rascal: Model
Na+
Optimized Model
Modified Model
Mg2+
Optimized Model

Secondary Structure

Structure monad0045-4

Parameter: CentroidFold: McCaskill(BL) 2^-2

Structure String: .((....(((((((((.......))))))))).....)).

Flip Position: *---------------*******----------------*

Tertiary Structure: Rascal: Model
Na+
Optimized Model
Modified Model
Mg2+
Optimized Model

Secondary Structure

Structure monad0045-5

Parameter: CentroidFold: McCaskill(Tur) 2^-4

Structure String: (((....(((((((((.......))))))))).....)))

Flip Position: ----------------*--***-----------*------

Tertiary Structure: Rascal: Model
Na+
Optimized Model
Modified Model
Mg2+
Optimized Model

Secondary Structure