Detail of monad0036
Aptamer Detail
- monad ID
- monad0036
- Length
- 38
- Target Molecule
-
C5 (P01031)
- Sequence
- CGCCGCGGUCUCAGGCGCUGAGUCUGAGUUUACCUGCG
- Adaptation Disease
- Age-Related Macular Degeneration
- Product Name
- Zimura
- Phase
- II/III
- Remark
- A Phase II / III randomized, double-masked, controlled trial has been carried out to assess the safety and efficacy of intravitreous administration of Zimura (anti-C5 aptamer), in subjects with geographic atrophy secondary to dry age-related macular degeneration (AMD).
Structure monad0036-1
- Parameter
- CentroidFold: CONTRAFold 2^0
- Structure String
- .........(((((((.....)))))))..........
- Flip Position
- ********-------*-**--*------**********
- Tertiary Structure
-
Rascal: Model
Na+
Optimized Model
Modified Model
Mg2+
Optimized Model
- Secondary Structure
-
Structure monad0036-2
- Parameter
- CentroidFold: CONTRAFold 2^2
- Structure String
- ...(((((((((((((.....)))))))...))).)))
- Flip Position
- ****---*--------*****--------*-*------
- Tertiary Structure
-
Rascal: Model
Na+
Optimized Model
Modified Model
Mg2+
Optimized Model
- Secondary Structure
-
Structure monad0036-3
- Parameter
- CentroidFold: McCaskill BL 2^0
- Structure String
- .......(.(((((((.....)))))))....).....
- Flip Position
- *********--------****-------**********
- Tertiary Structure
-
Rascal: Model
Na+
Optimized Model
Modified Model
Mg2+
Optimized Model
- Secondary Structure
-
