Detail of monad0024
Aptamer Detail
- monad ID
- monad0024
- Length
- 27
- Target Molecule
-
VEGF (P15692)
- Sequence
- CGGAAUCAGUGAAUGCUUAUACAUCCG
- Adaptation Disease
- Wet Macular Degeneration neovascular age-related macular degeneration
- Product Name
- Pegaptanib
- Phase
- AD
- Remark
- Macugen is used for the treatment of angiogenic age-related macular degeneration (AMD).
Structure monad0024-1
- Parameter
- CentroidFold: CONTRAFold 2^2
- Structure String
- ((((...................))))
- Flip Position
- ------******************---
- Tertiary Structure
-
Rascal: Model
Na+
Optimized Model
Modified Model
Mg2+
Optimized Model
Structure monad0024-2
- Parameter
- CentroidFold: CONTRAFold 2^4
- Structure String
- ((((...(((....)))......))))
- Flip Position
- ----------****----****-----
- Tertiary Structure
-
Rascal: Model
Na+
Optimized Model
Modified Model
Mg2+
Optimized Model
Structure monad0024-3
- Parameter
- CentroidFold: CONTRAFold 2^6
- Structure String
- ((((((.(((....))).))...))))
- Flip Position
- -----------***------*------
- Tertiary Structure
-
Rascal: Model
Na+
Optimized Model
Modified Model
Mg2+
Optimized Model
Structure monad0024-4
- Parameter
- CentroidFold: McCaskill BL 2^2
- Structure String
- ((((....(......).......))))
- Flip Position
- ---------******---*-*------
- Tertiary Structure
-
Rascal: Model
Na+
Optimized Model
Modified Model
Mg2+
Optimized Model
Structure monad0024-5
- Parameter
- CentroidFold: McCaskill Turner 2^2
- Structure String
- ((((....((((....))))...))))
- Flip Position
- ---*****-----***----****---
- Tertiary Structure
-
Rascal: Model
Na+
Optimized Model
Modified Model
Mg2+
Optimized Model